(±)-CP 55,940 was one of the first bicyclic mimetics of Δ The racemic mixture of CP 55,940 is 20- to 100-fold more effective than Δ CP 55,940 has also been used to identify and characterize the central cannabinoid (CB1) receptor in rat brain membranes. The capacity to displace CP 55,940 from CB1 receptor in rat brain preparations has frequently been used in the characterization of novel cannabimimetics.
1.Howlett, A.C.,Johnson, M.R.,Melvin, L.S., et al. Nonclassical cannabinoid analgetics inhibit adenylate cyclase: Development of a cannabinoid receptor model. Molecular Pharmacology 33, 297-302 (1987).