(R)-Methotrimeprazine


CAS No. : 60-99-1

(R)-Methotrimeprazine,60-99-1
Product Details
Cat No:R063939
Synonyms:(R)-2-Methoxy-N,N,β-trimethyl-10H-phenothiazine-10-propanamine; (-)-10-[3-(Dimethylamino)-2-methylpropyl]-2-methoxy-phenothiazine; 2-Methoxytrimeprazine; 7044 R.P.; CL 36467; CL 39743; Hirnamin; Levomeprazine; Levomepromazin; Levomepromazine; Levopr
Molecular Formula:C19H24N2OS
Molecular Weight:328.474
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Appearance:Solid powder
Purity: > 98%
Cat No:R063939
Cas No:60-99-1
Product-Name:(R)-Methotrimeprazine
IUPAC Name:(2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
InChI:InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1
InChIKey:VRQVVMDWGGWHTJ-CQSZACIVSA-N
SMILES:CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C
Levomepromazine, also known as methotrimeprazine, is a phenothiazine neuroleptic drug. Levomepromazine is used for the treatment of psychosis, particularly those of schizophrenia, and manic phases of bipolar disorder.
1:Clin Oncol (R Coll Radiol). 1995;7(4):268-9. Ulcerative skin reaction from subcutaneous infusion of isotonic methotrimeprazine and diamorphine.Hatton MQ,McMurray A,Harnett AN, PMID: 8845330
Abstract: We report an ulcerative skin reaction resulting from a subcutaneous infusion of isotonic methotrimeprazine and diamorphine. Skin reactions are a recognized side effect of this treatment, although they are reduced by the use of the isotonic formulation of methotrimeprazine. Frank ulceration has not been previously reported. It occurred in our patient despite low doses of diamorphine and methotrimeprazine, an isotonic formulation, and a short infusion time.
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