1,2-Dimyristoyl-sn-glycero-3-phosphate (sodium salt)

CAS No. : 80724-31-8

1,2-Dimyristoyl-sn-glycero-3-phosphate (sodium salt),80724-31-8
Product Details
Cat No:R061387
Synonyms:1,1’-[(1R)-1-[(Phosphonooxy)methyl]-1,2-ethanediyl] Ester Tetradecanoic Acid Sodium Salt; (1R)-1-[(Phosphonooxy)methyl]-1,2-ethanediyl Ester Tetradecanoic Acid Monosodium Salt; 1,2-Dimyristoyl-sn-glycero-3-phosphate Monosodium Salt; Monosodium 1,2-Di
Molecular Formula:C31H60O8P • Na
Molecular Weight:614.8
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Unit:100 mg
Physical Appearance:solid
Cat No:R061387
Cas No:80724-31-8
Product-Name:1,2-Dimyristoyl-sn-glycero-3-phosphate (sodium salt)
Phosphatidic acids (PAs) can be formed by the acylation of lysophosphatidic acids, the phosphorylation of diacylglycerols, or the removal of the choline group from phosphatidylcholine. They have important roles in intracellular and extracellular signaling. 1,2-Dimyristoyl-sn-glycero-3-phosphate is a phospholipid containing the long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It may be useful in evaluating the role of PAs in micelles, liposomes, and artificial membranes.

1. J. Faraudo and A. Travesset “Phosphatidic Acid Domains in Membranes: Effect of Divalent Counterions” Biophysical Journal, Vol. 92 pp. 2806-2818, 2007
2. E. Kooijman et al. “Modulation of Membrane Curvature by Phosphatidic Acid and Lysophosphatidic Acid” Traffic, Vol. 4(3) pp. 162-174, 2003
3. K. Athenstaedt and G. Daum “Phosphatidic acid, a key intermediate in lipid metabolism” European Journal of Biochemistry, Vol. 266 pp. 1-16, 1999
4. M. Hodgkin et al. “Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?” Trends in Biochemical Sciences, Vol. 23(6) pp. 200-204, 1998
5. A. Gimenez et al. “Regulation of Phosphatidic Acid Levels in Trypanosoma cruzi” Lipids, vol. 46 pp. 969-979, 2011

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