Appearance: yellow crystalline solid.
Purity by HPLC: ≥98% ; refer to CoA for more data
Purity By TLC: >99% ; multiple methods; refer for CoA for details.
Melting point: 173ºC - 174ºC
Solubility test: Clear yellow solution at 10mg/ml Dichloromethane
Cat No: | R050011 |
Cas No: | 518-75-2 |
Product-Name: | (-)-Citrinin |
IUPAC Name: | (3R,4S)-6-hydroxy-3,4,5-trimethyl-8-oxo-3,4-dihydroisochromene-7-carboxylic acid |
InChI: | InChI=1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,14H,1-3H3,(H,16,17)/t5-,7-/m1/s1 |
InChIKey: | CBGDIJWINPWWJW-IYSWYEEDSA-N |
SMILES: | CC1C(OC=C2C1=C(C(=C(C2=O)C(=O)O)O)C)C |
Citrinin (CAS 518-75-2) is a mycotoxin capable of inducing mitochondrial permeability transition. Citrinin also inhibits microtubule polymerization.
1.Flajs, Dubravka, and Maja Peraica. "Toxicological properties of citrinin." Archives of Industrial Hygiene and Toxicology 60.4 (2009): 457-464.
2.Chang, Chia-Hao, et al. "Mycotoxin citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration associated with disruption of microtubule formation in human cells." Toxicological Sciences 119.1 (2011): 84-92.
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