(11Z)-16-[[2-(Methylamino)-2-oxoacetyl]amino]-11-hexadecenoic Acid


CAS No. : 1235543-17-5

(11Z)-16-[[2-(Methylamino)-2-oxoacetyl]amino]-11-hexadecenoic Acid,1235543-17-5
Product Details
Cat No:R040201
Synonyms:16-[[2-(Methylamino)-2-oxoacetyl]amino]-hexadecen-11-oic Acid; 16-[[2-(Methylamino)-2-oxoacetyl]amino]-11-hexadecenoic Acid; CAY10665
Molecular Formula:C19H34N2O4
Molecular Weight:354.491
Price:Get quote
We would like to match the lowest price on market if possible.

Your information is safe with us.

refresh

Assay:≥98%
Appearance:A solution in ethanol
Cat No:R040201
Cas No:1235543-17-5
Product-Name:(11Z)-16-[[2-(Methylamino)-2-oxoacetyl]amino]-11-hexadecenoic Acid
IUPAC Name:(Z)-16-[[2-(methylamino)-2-oxoacetyl]amino]hexadec-11-enoic acid
InChI:InChI=1S/C19H34N2O4/c1-20-18(24)19(25)21-16-14-12-10-8-6-4-2-3-5-7-9-11-13-15-17(22)23/h6,8H,2-5,7,9-16H2,1H3,(H,20,24)(H,21,25)(H,22,23)/b8-6-
InChIKey:WKESFWWKRDQART-VURMDHGXSA-N
SMILES:CNC(=O)C(=O)NCCCCC=CCCCCCCCCCC(=O)O
Isolated neonatal rat cardiomyocytes, which spontaneously beat in culture, are used to evaluate the antiarrhythmic effects of polyunsaturated fatty acids (PUFA). In this model, the ω-3 PUFA eicosapentaenoic acid (EPA, 3-10 μM) reduces the contraction rate of cells, indicating a positive antiarrhythmic effect. Cytochrome P450 metabolites of EPA are more potent, with 17,18-epoxyeicosatetraenoic acid (17,18-EET) reducing contractions at 30 nM. CAY10665 is a bioisostere of 17,18-EET which is approximately 50% more effective at reducing arrhythmic contraction frequency, without affecting amplitude, when tested at 30 nM. This disubstituted oxamide represents a stable analog of 17,18-EET which may be used to study the mechanism of regulation of cardiomyocyte contractility by EPA metabolites.
Recommended Products
  • CAS No. :1354695-82-1
    Product Name:

    ent-Entecavir-di-o-benzyl Ether

    Cat No: R062274 View details
  • CAS No. :403648-76-0
    Product Name:

    4-(Difluoromethyl)-phenol

    Cat No: R062275 View details
  • CAS No. :NA
    Product Name:

    Linagliptin Methyldimer-d6

    Cat No: R062276 View details
  • CAS No. :NA
    Product Name:

    Linagliptin Ethyldimer

    Cat No: R062277 View details