Gestonorone


CAS No. : 2137-18-0

Gestonorone,2137-18-0
Product Details
Cat No:R019895
Synonyms:17-Hydroxy-19-norpregn-4-ene-3,20-dione; 17α-Hydroxy-19-norpregn-4-ene-3,20-dione; 17α-Hydroxy-19-norprogesterone; Gestonorone; TX 045
Molecular Formula:C20H28O3
Molecular Weight:316.441
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Cat No:R019895
Cas No:2137-18-0
Product-Name:Gestonorone
IUPAC Name:(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
InChI:InChI=1S/C20H28O3/c1-12(21)20(23)10-8-18-17-5-3-13-11-14(22)4-6-15(13)16(17)7-9-19(18,20)2/h11,15-18,23H,3-10H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1
InChIKey:GTFUITFQDGVJSK-XGXHKTLJSA-N
SMILES:CC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34)C)O
Gestronol (BAN), also known as gestonorone, as well as 17α-hydroxy-19-norprogesterone or 17α-hydroxy-19-norpregn-4-ene-3,20-dione, is a steroidal progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups that was never marketed. The C17α caproate ester of gestronol, gestonorone caproate (gestronol hexanoate), in contrast, has been marketed.
1: Lopatkin N, Darenkow A, Sahmatow J, Tankó A, Ignaschin N, Warentsow G. [Gestonorone therapy of prostatic adenoma]. Acta Chir Acad Sci Hung. 1980;21(4):271-8. German. PubMed PMID: 6175122.
2: Luciani L, Frizzi V. [On a new synthetic gestagen, gestonorone. Its use in the treatment of prostatic hypertrophy and histological control of its effects on the male gonad]. Minerva Urol. 1969 Nov-Dec;21(6):203-13. Italian. PubMed PMID: 4104300.
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