(±)14(15)-EpEDE


CAS No. : 351533-80-7

(±)14(15)-EpEDE,351533-80-7
Product Details
Cat No:R017337
Synonyms:(±)14,15-Epoxyeicosadienoic Acid
Molecular Formula:C20H34O3
Molecular Weight:322.489
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Cat No:R017337
Cas No:351533-80-7
Product-Name:(±)14(15)-EpEDE
IUPAC Name:(8Z,11Z)-13-(3-pentyloxiran-2-yl)trideca-8,11-dienoic acid
InChI:InChI=1S/C20H34O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6,10,13,18-19H,2-3,5,7-9,11-12,14-17H2,1H3,(H,21,22)/b6-4-,13-10-
InChIKey:ZXBWLXDDSYHRTE-QGIBGKBZSA-N
SMILES:CCCCCC1C(O1)CC=CCC=CCCCCCCC(=O)O
8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid (Item No. 90230), is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action of fatty acid elongases. It can be metabolized by the cyclooxygenase pathway to produce 1-series prostaglandins (PGs) (e.g., PGE1). (±)14(15)-EpEDE is an EpEDE acid formed from 8,11,14-eicosatrienoic acid. This monoepoxide can be generated from the PUFA, in vitro, by the action of a strong oxidizing agent. Alternatively, this compound may be produced, in vivo, by epoxidation of the PUFA by cytochrome P450 epoxygenases. The biological properties of this compound are poorly understood.
1.Levin, G.,Duffin, K.L.,Obukowicz, M.G., et al. Differential metabolism of dihomo-γ-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: Implications for cellular synthesis of prostaglandin E1 and prostaglandin E2. Biochemistry
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