(-)-Corey Lactone Diol

CAS No. : 32233-40-2

(-)-Corey Lactone Diol ,32233-40-2
Product Details
Cat No:R016542
Synonyms:(3aR,4S,5R,6aS)Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one; [3aR-(3aα,4α,5β,6aα)]Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one;
Molecular Formula:C8H12O4
Molecular Weight:172.18
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Appearance:A crystalline solid
Cat No:R016542
Cas No:32233-40-2
Product-Name:(-)-Corey Lactone Diol
IUPAC Name:(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one
Corey aldehyde is a versatile, hydroxy-lactone intermediate for the synthesis of prostaglandins and prostaglandin analogs. Prostaglandin derivatives with modifications in the α chain, the ω chain, or both, are readily accessible from this general intermediate. (−)-Corey lactone diol is simply the reduced version of Corey aldehyde, with alcohol groups at both C-11 and C-13. This allows the introduction of ω chain constituents via alternate chemistries, such as nucleophilic displacements.
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