(±)11(12)-DiHET Lipid Maps® MS Standard


CAS No. :

(±)11(12)-DiHET Lipid Maps® MS Standard,
Product Details
Cat No:R016337
Synonyms:(±)11,12-DiHETrE
Molecular Formula:C20H34O4
Molecular Weight:338.5
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Cat No:R016337
Product-Name:(±)11(12)-DiHET Lipid Maps® MS Standard
InChI:InChI=1S/C20H34O4/c1-2-3-4-5-9-12-15-18(21)19(22)16-13-10-7-6-8-11-14-17-20(23)24/h6,8-10,12-13,18-19,21-22H,2-5,7,11,14-17H2,1H3,(H,23,24)/b8-6-,12-9-,13-10-/t18-,19+/m1/s1
InChIKey:LRPPQRCHCPFBPE-LZXKBWHHSA-N
SMILES:CCCCC/C=CC[C@@H](O)[C@@H](O)C/C=CC/C=CCCCC(O)=O
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)11(12)-DiHET relaxes U46619 (Item No. 16450)-contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET (Item No. 50511).
1.Oliw, E.H.,Guengerich, F.P., and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. The Journal of Biological Chemisty 257, 3771-3781 (1982).
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