Assay:≥98%
Appearance:A crystalline solid
Cat No: | R016219 |
Cas No: | 1258-84-0 |
Product-Name: | Pristimerin |
IUPAC Name: | methyl (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylate |
InChI: | InChI=1S/C30H40O4/c1-18-19-8-9-22-28(4,20(19)16-21(31)24(18)32)13-15-30(6)23-17-27(3,25(33)34-7)11-10-26(23,2)12-14-29(22,30)5/h8-9,16,23,32H,10-15,17H2,1-7H3/t23-,26-,27-,28+,29-,30+/m1/s1 |
InChIKey: | JFACETXYABVHFD-RKHSXEAASA-N |
SMILES: | O=C1C(O)=C(C)C2=CC=C([[email protected]](CC[[email protected]]3(C)C4C[[email protected]@](C(OC)=O)(C)CC3)(C)[[email protected]@]4(C)CC5)[[email protected]]5(C)C2=C1 |
Pristimerin(CAS 1258-84-0) is a natural product derived from the Celastraceae and Hippocrateaceae families that were used as folk medicines for anti inflammation in ancient times. It has been shown that pristimerin induces apoptosis in breast cancer cells.
1: Yang H, Landis-Piwowar KR, Lu D, Yuan P, Li L, Reddy GP, Yuan X, Dou QP. Pristimerin induces apoptosis by targeting the proteasome in prostate cancer cells. J Cell Biochem. 2008 Jan 1;103(1):234-44. PubMed PMID: 17541980.
2: Luo DQ, Wang H, Tian X, Shao HJ, Liu JK. Antifungal properties of pristimerin and celastrol isolated from Celastrus hypoleucus. Pest Manag Sci. 2005 Jan;61(1):85-90. PubMed PMID: 15593077.
3: Monache FD, Bettólo GV, de Lima OG, D/'Albuquerque IL, de Barros Coêlho JS. The structure of tingenone, a quinonoid triterpene related to pristimerin. J Chem Soc Perkin 1. 1973;22:2725-8. PubMed PMID: 4799459.
Your information is safe with us.