(S)-Zearalanone


CAS No. : 5975-78-0

(S)-Zearalanone,5975-78-0
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:R011064
Synonyms:(3S)-3,4,5,6,9,10,11,12-Octahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; 6-(10-hydroxy-6-oxoundecyl)-β-resorcylic Acid µ-Lactone; P 1502; Zanone; Zearalanone; ZAN;
Molecular Formula:C18H24O5
Molecular Weight:320.385
Target:Estrogen/progestogen Receptor
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Appearance:White solid
Cat No:R011064
Cas No:5975-78-0
Product-Name:(S)-Zearalanone
IUPAC Name:(11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-7,13-dione
InChI:InChI=1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1
InChIKey:APJDQUGPCJRQRJ-LBPRGKRZSA-N
SMILES:CC1CCCC(=O)CCCCCC2=CC(=CC(=C2C(=O)O1)O)O

Zearalanone is a minor component of the zearalenone complex produced by several species of Fusarium. Like the more abundant analogues, zearalanone causes estrogenic effects in domestic livestock. Zearalanone is a metabolite of α-zearalanol, a commercially available growth promotant in animals, and is a useful standard for detection of zearanol-contaminated products and Fusarium-contaminated grains.

Metabolism of zearalenone by Fusarium roseum graminearum. Steele J.A. et al. J. Agr. Food Chem. 1976, 24, 89.


Zearanol metabolism by subcellular fractions from lamb liver. Pompa G. et al. J. Vet. Pharmacol. Ther. 1988, 11, 197.

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