(2S)-OMPT


CAS No. : 1217471-69-6

(2S)-OMPT,1217471-69-6
Product Details
Cat No:R009590
Synonyms:(2S)-3-[(hydroxymercaptophosphinyl)oxy]-2-methoxypropyl ester, 9Z-octadecenoic acid, triethyl ammonium salt
Molecular Formula:C22H43O6PS • 2(C2H5)3N
Molecular Weight:669.0
Price:Get quote
We would like to match the lowest price on market if possible.

Your information is safe with us.

refresh
Cat No:R009590
Cas No:1217471-69-6
Product-Name:(2S)-OMPT
InChI:InChI=1S/C22H43O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)27-19-21(26-2)20-28-29(24,25)30/h10-11,21H,3-9,12-20H2,1-2H3,(H2,24,25,30)/b11-10-/t21-/m0/s1
InChIKey:FCVJYKICQNLXAX-XPTLAUCJSA-N
SMILES:O=C(OC[C@H](OC)COP(O)(O)=S)CCCCCCC/C=CCCCCCCCC
Lysophosphatidic acid (LPA) is a potent lipid mediator that elicits its effect through four distinct receptors - LPA1/EDG-2, LPA2/EDG-4, LPA3/EDG-7 and LPA4/GPR23. OMPT is a selective agonist of the lysophosphatidic acid 3 (LPA3) receptor. It exhibits EC50 values of 68 nM and >6.8 µM for calcium mobilization in LPA1 and LPA2-expressing Sf9 cells, respectively. The (2S)-OMPT enantiomer is 5- to 20-fold more active than (2R)-OMPT in calcium release assays in both LPA3-transfected Sf9 and rat hepatoma Rh7777 cells.
1.Chun, J.,Goetzl, E.J.,Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacological Reviews 54, 265-269 (2002).
Recommended Products
  • CAS No. :150321-87-2
    Product Name:

    N-(4-(6-DIMETHYLAMINO-2-BENZOFURANYL)PHENYL)ISOTHIOCYANATE

    Cat No: M104101 View details
  • CAS No. :153257-97-7
    Product Name:

    Benzene, 1,3-difluoro-5-(1-propynyl)- (9CI)

    Cat No: M104104 View details
  • CAS No. :142062-55-3
    Product Name:

    BIM189

    Cat No: M104105 View details
  • CAS No. :153943-61-4
    Product Name:

    Cyclopropanecarboxylic acid, 1-ethynyl-2-methyl-, methyl ester, trans- (9CI)

    Cat No: M104106 View details