(+)-5-trans Cloprostenol


CAS No. : 57968-81-7

(+)-5-trans Cloprostenol,57968-81-7
Product Details
Cat No:R009133
Synonyms:D-Cloprostenol;(+)-5,6-trans Cloprostenol;(+)-5-trans-16-m-chlorophenoxy tetranor PGF2α;(+)-5-trans-16-m-chlorophenoxy tetranor Prostaglandin F2α
Molecular Formula:C22H29ClO6
Molecular Weight:424.9
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Cat No:R009133
Cas No:57968-81-7
Product-Name:(+)-5-trans Cloprostenol
InChI:InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1+,11-10+/t16-,18-,19-,20+,21-/m1/s1
InChIKey:VJGGHXVGBSZVMZ-BDFMIYKPSA-N
SMILES:OC1[C@H](C/C=C/CCCC(O)=O)[C@@H](/C=C/[C@@H](O)COC2=CC(Cl)=CC=C2)C(O)C1
Cloprostenol is a synthetic derivative of prostaglandin F that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of (+)-cloprostenol. The (+)-5-trans isomer is 20-fold less active than the 5-cis form in terminating pregnancy in the hamster.
1.Bowler, J.,Brown, E.D.,Crossley, N.S., et al. Double bond isomers of cloprostenol. Prostaglandins 17(6), 789-800 (1979).
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