(2S)-2-Ethyl-8-methyl-1-thia-4,8-diazaspiro[4,5]decan-3-one


CAS No. : 503431-81-0

(2S)-2-Ethyl-8-methyl-1-thia-4,8-diazaspiro[4,5]decan-3-one,503431-81-0
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:R007567
Synonyms:AF 267B;
Molecular Formula:C10H18N2OS
Molecular Weight:214.327
Target:muscarinic M1 agonist
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Appearance:Solid powder
Purity: > 98%
Cat No:R007567
Cas No:503431-81-0
Product-Name:(2S)-2-Ethyl-8-methyl-1-thia-4,8-diazaspiro[4,5]decan-3-one
IUPAC Name:(2S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one
InChI:InChI=1S/C10H18N2OS/c1-3-8-9(13)11-10(14-8)4-6-12(2)7-5-10/h8H,3-7H2,1-2H3,(H,11,13)/t8-/m0/s1
InChIKey:PHOZOHFUXHPOCK-QMMMGPOBSA-N
SMILES:CCC1C(=O)NC2(S1)CCN(CC2)C
NGX-267 is a muscarinic M1 agonist potentially for the treatment of Xerostomia, Alzheimer/'s disease and cognitive

1: Heinrich JN, Butera JA, Carrick T, Kramer A, Kowal D, Lock T, Marquis KL,
Pausch MH, Popiolek M, Sun SC, Tseng E, Uveges AJ, Mayer SC. Pharmacological
comparison of muscarinic ligands: historical versus more recent muscarinic
M1-preferring receptor agonists. Eur J Pharmacol. 2009 Mar 1;605(1-3):53-6. doi:
10.1016/j.ejphar.2008.12.044. PubMed PMID: 19168056.

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