(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt


CAS No. : 102418-74-6

(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt,102418-74-6
Product Details
Cat No:R003009
Synonyms:4-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]benzoic Acid Sodium Salt; N-Biotinyl-p-aminobenzoic Acid Sodium Salt;
Molecular Formula:C17H20N3O4S • Na
Molecular Weight:385.4
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Assay:≥98%
Appearance:A crystalline solid
Cat No:R003009
Cas No:102418-74-6
Product-Name:(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt
InChIKey:AMXZKFYBAOWERX-HZPCBCDKSA-M
(+)-Biotin 4-amidobenzoic acid is a substrate of biotinidase, which cleaves biotin amide to give biotin in vivo. Biotin is an essential coenzyme for certain carboxylases and is used to modify histones and regulate gene transcription. Biotinidase has key roles in intestinal absorption of biotin, the transport of biotin in plasma, and in the regulation of histone biotinylation. (+)-Biotin 4-amidobenzoic acid is hydrolyzed by biotinidase to release 4-aminobenzoic acid (PABA), which can be quantified by either fluorescent or colorimetric methods. This approach is used in biotinidase activity assays in newborn screening protocols to evaluate biotinidase deficiency.
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