1-Aminocyclopropane-1-carboxylic Acid


CAS No. : 22059-21-8

1-Aminocyclopropane-1-carboxylic Acid,22059-21-8
Product Details
Cat No:R000007
Synonyms:1-Aminocyclopropanecarboxylic Acid; 1-Amino-1-carboxycyclopropane; 1-Aminocyclopropane-1-carboxylate; 1-Aminocyclopropanecarboxylic Acid; ACC; ACPC; NSC 98430; α-Aminocyclopropanecarboxylic Acid;
Molecular Formula:C4H7NO2
Molecular Weight:101.105
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Assay:≥98%
Appearance:A crystalline solid
Cat No:R000007
Cas No:22059-21-8
Product-Name:1-Aminocyclopropane-1-carboxylic Acid
IUPAC Name:1-aminocyclopropane-1-carboxylic acid
InChI:InChI=1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
InChIKey:PAJPWUMXBYXFCZ-UHFFFAOYSA-N
SMILES:C1CC1(C(=O)O)N
1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate. This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.
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