Testosterone Propionate

CAS No. : 57-85-2

Testosterone Propionate,57-85-2
Product Details
Cat No:M144116
Synonyms:17β-Hydroxy-4-androsten-3-one 17-propionate, 17β-Propionyloxy-4-androsten-3-one, 4-Androsten-17β-ol-3-one 17-propionate
Molecular Formula:C22H32O3
Molecular Weight:344.49
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Cat No:M144116
Cas No:57-85-2
Product-Name:Testosterone Propionate
MDL No:MFCD00003653
Testosterone Propionate is a pure testosterone hormone. Although synthetic it is a perfect replica of the primary naturally produced male androgen testosterone. By design, the hormone is attached to the Propionate (propionic acid) ester, a small/short ester that enables the hormone’s release time to be controlled. Without an ester, the hormone would disperse and dissipate rapidly post administration. By attaching the ester, this promotes a controlled release and allows the individual to inject the hormone less frequently. Once Testosterone Propionate is injected, the ester slowly begins to detach from the hormone. As the ester is detached the testosterone hormone begins to release into the blood. The half-life of Testosterone Propionate is approximately two days, which is substantially longer than ester free testosterone, which carries a half-life a little less than 24 hours.
1: Akanni OO, Abiola OJ, Adaramoye OA. Methyl Jasmonate Ameliorates Testosterone Propionate-induced Prostatic Hyperplasia in Castrated Wistar Rats. Phytother Res. 2017 Apr;31(4):647-656. doi: 10.1002/ptr.5778. Epub 2017 Feb 16. PubMed PMID: 28211173.
2: Chaudhari NK, Nampoothiri LP. Neurotransmitter alteration in a testosterone propionate-induced polycystic ovarian syndrome rat model. Horm Mol Biol Clin Investig. 2017 Feb 1;29(2):71-77. doi: 10.1515/hmbci-2016-0035. PubMed PMID: 27802175.
3: Wang L, Kang Y, Zhang G, Zhang Y, Cui R, Yan W, Tan H, Li S, Wu B, Cui H, Shi G. Deficits in coordinated motor behavior and in nigrostriatal dopaminergic system ameliorated and VMAT2 expression up-regulated in aged male rats by administration of testosterone propionate. Exp Gerontol. 2016 Jun;78:1-11. doi: 10.1016/j.exger.2016.03.003. Epub 2016 Mar 5. PubMed PMID: 26956479.
4: Zhang G, Li S, Kang Y, Che J, Cui R, Song S, Cui H, Shi G. Enhancement of dopaminergic activity and region-specific activation of Nrf2-ARE pathway by intranasal supplements of testosterone propionate in aged male rats. Horm Behav. 2016 Apr;80:103-16. doi: 10.1016/j.yhbeh.2016.02.001. Epub 2016 Feb 15. PubMed PMID: 26893122.
5: Qiu L, Zhao Y, Guo Q, Zhang Y, He L, Li W, Zhang J. Dose-dependent regulation of steroid receptor coactivator-1 and steroid receptors by testosterone propionate in the hippocampus of adult male mice. J Steroid Biochem Mol Biol. 2016 Feb;156:23-31. doi: 10.1016/j.jsbmb.2015.11.012. Epub 2015 Nov 26. PubMed PMID: 26607693.
6: Nakachi Y, Iseki M, Yokoo T, Mizuno Y, Okazaki Y. Gene expression profile of the neonatal female mouse brain after administration of testosterone propionate. J Sex Med. 2015 Apr;12(4):887-96. doi: 10.1111/jsm.12802. Epub 2015 Jan 28. PubMed PMID: 25630233.
7: Allen DT, Saaka Y, Lawrence MJ, Lorenz CD. Atomistic description of the solubilisation of testosterone propionate in a sodium dodecyl sulfate micelle. J Phys Chem B. 2014 Nov 20;118(46):13192-201. doi: 10.1021/jp508488c. Epub 2014 Nov 7. PubMed PMID: 25343221.
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