(2R,4S)-4-(2H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid


CAS No. : 125546-04-5

(2R,4S)-4-(2H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid,125546-04-5
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:M119132
Synonyms:(2S,4R)-4-((2H-tetrazol-5-yl)methyl)piperidine-2-carboxylic acid
Molecular Formula:C8H13N5O2
Molecular Weight:211.225
Target:NMDA Receptor
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Appearance:Solid powder
Purity: > 98%
Cat No:M119132
Cas No:125546-04-5
Product-Name:(2R,4S)-4-(2H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid
IUPAC Name:(2S,4R)-4-(2H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid
InChI:InChI=1S/C8H13N5O2/c14-8(15)6-3-5(1-2-9-6)4-7-10-12-13-11-7/h5-6,9H,1-4H2,(H,14,15)(H,10,11,12,13)/t5-,6+/m1/s1
InChIKey:FAAVTENFCLADRE-RITPCOANSA-N
SMILES:C1CNC(CC1CC2=NNN=N2)C(=O)O
LY233053 is a structurally novel, potent and selective competitive N-methyl-D-aspartate receptor antagonist.

1: Madden KP, Clark WM, Kochhar A, Zivin JA. Efficacy of LY233053, a competitive glutamate antagonist, in experimental central nervous system ischemia. J Neurosurg. 1992 Jan;76(1):106-10. PubMed PMID: 1727148.
2: Schoepp DD, Ornstein PL, Leander JD, Lodge D, Salhoff CR, Zeman S, Zimmerman DM. Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action. J Pharmacol Exp Ther. 1990 Dec;255(3):1301-8. PubMed PMID: 2148188.
3: Ornstein PL, Schoepp DD, Leander JD, Wong T, Zimmerman DM, Lodge D. LY233053: a structurally novel, potent and selective competitive N-methyl-D-aspartate receptor antagonist. Prog Clin Biol Res. 1990;361:429-33. PubMed PMID: 2149764.

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