(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID


CAS No. : 127910-31-0

(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID,127910-31-0
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:M116301
Synonyms:(E)-2-amino-4-methyl-5-phosphonopent-3-enoic acid
Molecular Formula:C6H12NO5P
Molecular Weight:209.138
Target:NMDA Receptor
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Appearance:Solid powder
Purity: > 98%
Cat No:M116301
Cas No:127910-31-0
Product-Name:(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
IUPAC Name:(E)-2-amino-4-methyl-5-phosphonopent-3-enoic acid
InChI:InChI=1S/C6H12NO5P/c1-4(3-13(10,11)12)2-5(7)6(8)9/h2,5H,3,7H2,1H3,(H,8,9)(H2,10,11,12)/b4-2+
InChIKey:BDYHNCZIGYIOGJ-DUXPYHPUSA-N
SMILES:CC(=CC(C(=O)O)N)CP(=O)(O)O
CGP37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). CGP37849 is an anticonvulsive following oral administration in vivo.

1. Loscher and Honack (1991) Anticonvulsant and behavioural effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine. J.Pharmacol.Exp.Ther. 256 432. PMID: 1671593.
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