(2R,3R)-2,3-dihydroxybutanedioic acid

CAS No. : 134865-37-5

(2R,3R)-2,3-dihydroxybutanedioic acid,134865-37-5
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:M107484
Synonyms:(2R,3R)-2,3-dihydroxybutanedioic acid
Molecular Formula:C16H24ClNO8
Molecular Weight:393.817
Target:β2 adrenergic receptor agonist
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Appearance:Solid powder
Purity: > 98%
Cat No:M107484
Cas No:134865-37-5
Product-Name:(2R,3R)-2,3-dihydroxybutanedioic acid
IUPAC Name:4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-3-chlorophenol;(2R,3R)-2,3-dihydroxybutanedioic acid
Meluadrine, also known as (R)-Tulobuterol; Tulobuterol-(R); HSR-81 (R); HSR-81, is an β2 adrenergic receptor agonist potentially use to prevent preterm labor.
1:Acta Crystallogr C. 2013 Jun;69(Pt 6):658-64. doi: 10.1107/S0108270113012377. Epub 2013 May 17. Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid.Benylles A,Cairns D,Cox PJ,Kay G, PMID: 23744391 DOI: 10.1107/S0108270113012377
Abstract: Reaction between cysteamine (systematic name: 2-aminoethanethiol, C2H7NS) and L-(+)-tartaric acid [systematic name: (2R,3R)-2,3-dihydroxybutanedioic acid, C4H6O6] results in a mixture of cysteamine tartrate(1-) monohydrate, C2H8NS(+)·C4H5O6(-)·H2O, (I), and cystamine bis[tartrate(1-)] dihydrate, C4H14N2S2(2+)·2C4H5O6(-)·2H2O, (III). Cystamine [systematic name: 2,2/'-dithiobis(ethylamine), C4H12N2S2], reacts with L-(+)-tartaric acid to produce a mixture of cystamine tartrate(2-), C4H14N2S2(2+)·C4H4O6(2-), (II), and (III). In each crystal structure, the anions are linked by O-H···O hydrogen bonds that run parallel to the a axis. In addition, hydrogen bonding involving protonated amino groups in all three salts, and water molecules in (I) and (III), leads to extensive three-dimensional hydrogen-bonding networks. All three salts crystallize in the orthorhombic space group P2(1)2(1)2(1).
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