(S)-Aminoglutethimide tartrate


CAS No. : 62268-19-3

(S)-Aminoglutethimide tartrate,62268-19-3
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I014673
Synonyms:(S)-Aminoglutethimide tartrate;;(S)-3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione (2R,3R)-2,3-dihydroxysuccinate
Molecular Formula:C17H22N2O8
Molecular Weight:382.36
Target:aromatase inhibitor
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Appearance:Solid powder
Purity: > 98%
Cat No:I014673
Cas No:62268-19-3
Product-Name:(S)-Aminoglutethimide tartrate
InChI:InChI=1S/C13H16N2O2.C4H6O6/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9;5-1(3(7)8)2(6)4(9)10/h3-6H,2,7-8,14H2,1H3,(H,15,16,17);1-2,5-6H,(H,7,8)(H,9,10)/t13-;1-,2-/m01/s1
InChIKey:DQUXPVVSVXIQNE-TZXXFBNGSA-N
SMILES:O=C([C@](CC)(C1=CC=C(N)C=C1)CC2)NC2=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O
(S)-Aminoglutethimide tartrate is an aromatase inhibitor. Also blocks adrenal steroidogenesis.

1: Hartmann RW, Bayer H, Grün G, Sergejew T, Bartz U, Mitrenga M. Pyridyl-substituted tetrahydrocyclopropa[a]naphthalenes: highly active and selective inhibitors of P450 arom. J Med Chem. 1995 Jun 9;38(12):2103-11. PubMed PMID: 7783141.
2: Whipple CA, Grodzicki RL, Hourihan J, Salhanick HA. Effects of cholesterol side chain cleavage inhibitors on 11 beta-hydroxylation: linkage of mitochondrial oxygenase systems. Steroids. 1981 Jun;37(6):673-9. PubMed PMID: 6974914.
3: Finch N, Dziemian R, Cohen J, Steinetz BG. The absolute configuration of the enantiomers of glutethimide and aminoglutethimide. Experientia. 1975 Sep 15;31(9):1002-3. PubMed PMID: 1175729.

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