(L)-Canavanine


CAS No. : 543-38-4

(L)-Canavanine,543-38-4
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I014430
Synonyms:(L)-Canavanine; AI3-52153; AI3 52153; AI352153;Butyric acid, 2-amino-4-(guanidinooxy)-, L-
Molecular Formula:C5H12N4O3
Molecular Weight:176.18
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Appearance:Solid powder
Purity: > 98%
Cat No:I014430
Cas No:543-38-4
Product-Name:(L)-Canavanine
InChI:InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9)
InChIKey:FSBIGDSBMBYOPN-UHFFFAOYSA-N
SMILES:O=C(O)C(N)CCONC(N)=N
(L)-Canavanine has antimutagenic activity.

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8: Maneerat K, Yongkiettrakul S, Jiemsup S, Tongtawe P, Gottschalk M, Srimanote P. Expression and Characterization of Serotype 2 Streptococcus suis Arginine Deiminase. J Mol Microbiol Biotechnol. 2017;27(3):133-146. doi: 10.1159/000452952. Epub 2017 Apr 29. PubMed PMID: 28456803.
9: Mathieu C, Macêdo JP, Hürlimann D, Wirdnam C, Haindrich AC, Suter Grotemeyer M, González-Salgado A, Schmidt RS, Inbar E, Mäser P, Bütikofer P, Zilberstein D, Rentsch D. Arginine and Lysine Transporters Are Essential for Trypanosoma brucei. PLoS One. 2017 Jan 3;12(1):e0168775. doi: 10.1371/journal.pone.0168775. eCollection 2017. PubMed PMID: 28045943; PubMed Central PMCID: PMC5207785.
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11: Krasuska U, Andrzejczak O, Staszek P, Bogatek R, Gniazdowska A. Canavanine Alters ROS/RNS Level and Leads to Post-translational Modification of Proteins in Roots of Tomato Seedlings. Front Plant Sci. 2016 Jun 14;7:840. doi: 10.3389/fpls.2016.00840. eCollection 2016. PubMed PMID: 27379131; PubMed Central PMCID: PMC4905978.
12: Krasuska U, Ciacka K, Orzechowski S, Fettke J, Bogatek R, Gniazdowska A. Modification of the endogenous NO level influences apple embryos dormancy by alterations of nitrated and biotinylated protein patterns. Planta. 2016 Oct;244(4):877-91. doi: 10.1007/s00425-016-2553-z. Epub 2016 Jun 14. PubMed PMID: 27299743.
13: Krasuska U, Andrzejczak O, Staszek P, Borucki W, Gniazdowska A. Toxicity of canavanine in tomato (Solanum lycopersicum L.) roots is due to alterations in RNS, ROS and auxin levels. Plant Physiol Biochem. 2016 Jun;103:84-95. doi: 10.1016/j.plaphy.2016.03.005. Epub 2016 Mar 5. PubMed PMID: 26986929.
14: Nurcahyanti AD, Wink M. L-Canavanine Potentiates Cytotoxicity of Chemotherapeutic Drugs in Human Breast Cancer Cells. Anticancer Agents Med Chem. 2017;17(2):206-211. PubMed PMID: 26902604.
15: Nurcahyanti AD, Wink M. L-Canavanine potentiates the cytotoxicity of doxorubicin and cisplatin in arginine deprived human cancer cells. PeerJ. 2016 Jan 7;4:e1542. doi: 10.7717/peerj.1542. eCollection 2016. PubMed PMID: 26839743; PubMed Central PMCID: PMC4734457.
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17: Nyazika TK, Robertson VJ, Nherera B, Mapondera PT, Meis JF, Hagen F. Comparison of biotyping methods as alternative identification tools to molecular typing of pathogenic Cryptococcus species in sub-Saharan Africa. Mycoses. 2016 Mar;59(3):151-6. doi: 10.1111/myc.12444. Epub 2015 Dec 10. PubMed PMID: 26661484; PubMed Central PMCID: PMC4761295.
18: Nurcahyanti AD, Wink M. Cytotoxic potentiation of vinblastine and paclitaxel by L-canavanine in human cervical cancer and hepatocellular carcinoma cells. Phytomedicine. 2015 Dec 15;22(14):1232-7. doi: 10.1016/j.phymed.2015.10.007. Epub 2015 Oct 30. PubMed PMID: 26655405.
19: Ott AK, Locher L, Koch M, Deuerling E. Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiae. PLoS One. 2015 Nov 30;10(11):e0143457. doi: 10.1371/journal.pone.0143457. eCollection 2015. PubMed PMID: 26618777; PubMed Central PMCID: PMC4664479.
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