(R)-(-)-JQ1 Enantiomer

CAS No. : 1268524-71-5

(R)-(-)-JQ1 Enantiomer,1268524-71-5
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I013976
Molecular Formula:C₂₃H₂₅ClN₄O₂S
Molecular Weight:456.99
Target: Epigenetic Reader Domain
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Cat No:I013976
Cas No:1268524-71-5
Product-Name:(R)-(-)-JQ1 Enantiomer
(-)-JQ-1 is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (−)-JQ1 has no effect.
[1]. Filippakopoulos, et al. Selective inhibition of BET bromodomains. Nature. 2010 Dec 23;468(7327):1067-73.
[2]. Mahe M, et al. An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers. EMBO Mol Med. 2018 Feb 20. pii: e8163.
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