(-)-Cephaeline dihydrochloride

CAS No. : 5853-29-2

(-)-Cephaeline dihydrochloride,5853-29-2
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I013502
Molecular Formula:C₂₈H₄₀Cl₂N₂O₄
Molecular Weight:539.53
Target: Cytochrome P450
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Cat No:I013502
Cas No:5853-29-2
Product-Name:(-)-Cephaeline dihydrochloride
IUPAC Name:(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol;dihydrochloride
(-)-Cephaeline dihydrochloride is an enantiomer of Cephaeline dihydrochloride. Cephaeline dihydrochloride is a selective CYP2D6 inhibtor with IC50 of 121 μM.
[1]. Asano T, et al. Metabolism of ipecac alkaloids Cephaeline and Emetine by human hepatic microsomal cytochrome P450s, and their inhibitory effects on P450 enzyme activities. Biol Pharm Bull. 2001 Jun;24(6):678-82.
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