(Z)-FeCP-oxindole


CAS No. : 1137967-28-2

(Z)-FeCP-oxindole,1137967-28-2
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I010843
Synonyms:(Z)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one
Molecular Formula:C19H15FeNO
Molecular Weight:329.18
Target:VEGFR
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Cat No:I010843
Cas No:1137967-28-2
Product-Name:(Z)-FeCP-oxindole
IUPAC Name:cyclopenta-1,3-diene;3-(cyclopenta-2,4-dien-1-ylidenemethyl)-1H-indol-2-olate;iron(2+)
InChI:InChI=1S/C14H11NO.C5H5.Fe/c16-14-12(9-10-5-1-2-6-10)11-7-3-4-8-13(11)15-14;1-2-4-5-3-1;/h1-9,15-16H;1-5H;/q;-1;+2/p-1
InChIKey:MTGBTDOTYGXLBK-UHFFFAOYSA-M
SMILES:[CH-]1C=CC=C1.C1=CC=C2C(=C1)C(=C(N2)[O-])C=C3C=CC=C3.[Fe+2]
Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 220 nM). Displays anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10μM. 
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