(E)-FeCP-oxindole


CAS No. : 884338-18-5

(E)-FeCP-oxindole,884338-18-5
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I010842
Synonyms:(E)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one
Molecular Formula:C19H25FeNO+2
Molecular Weight:339.26
Target:VEGFR
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Cat No:I010842
Cas No:884338-18-5
Product-Name:(E)-FeCP-oxindole
IUPAC Name:cyclopentane;(3E)-3-(cyclopentylmethylidene)-1H-indol-2-one;iron(2+)
InChI:InChI=1S/C14H15NO.C5H10.Fe/c16-14-12(9-10-5-1-2-6-10)11-7-3-4-8-13(11)15-14;1-2-4-5-3-1;/h3-4,7-10H,1-2,5-6H2,(H,15,16);1-5H2;/q;;+2/b12-9+;;
InChIKey:JGKCUURLEMXRGX-ANOGCNOSSA-N
SMILES:C1CCCC1.C1CCC(C1)C=C2C3=CC=CC=C3NC2=O.[Fe+2]
Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 214 nM). Displays anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10μM. 
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