CAS No. : 227619-64-9

Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I010527
Synonyms:(±)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylic acid
Molecular Formula:C6H8N2O4
Molecular Weight:172.14
Target:Glutamate (EAAT) Transporters
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Cat No:I010527
Cas No:227619-64-9
Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [3H]D-aspartate release (IC50 = 1.6 μM) rather than [3H]L-glutamate uptake (IC50 = 18 μM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 43 and 8 μM respectively).��.
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