(S)-(+)-Dimethindene maleate


CAS No. : 136152-65-3

(S)-(+)-Dimethindene maleate,136152-65-3
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I010411
Synonyms:N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate
Molecular Formula:C24H28N2O4
Molecular Weight:408.498
Target:Muscarinic Receptor
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Cat No:I010411
Cas No:136152-65-3
Product-Name:(S)-(+)-Dimethindene maleate
IUPAC Name:(Z)-but-2-enedioic acid;N,N-dimethyl-2-[3-[(1S)-1-pyridin-2-ylethyl]-1H-inden-2-yl]ethanamine
InChI:InChI=1S/C20H24N2.C4H4O4/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20;5-3(6)1-2-4(7)8/h4-10,12,15H,11,13-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m1./s1
InChIKey:SWECWXGUJQLXJF-HFNHQGOYSA-N
SMILES:CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C.C(=CC(=O)O)C(=O)O
Enantiomer that is a subtype-selective M2 muscarinic receptor antagonist (pKi values are 7.08, 7.78, 6.70 and 7.00 for M1, M2, M3 and M4 receptors respectively). Also H1 histamine receptor antagonist (pKi = 7.48).
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