(RS)-APICA


CAS No. : 170847-18-4

(RS)-APICA,170847-18-4
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I010269
Synonyms:(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid
Molecular Formula:C10H12NO5P
Molecular Weight:257.182
Target:GluR
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Cat No:I010269
Cas No:170847-18-4
Product-Name:(RS)-APICA
IUPAC Name:1-amino-5-phosphono-2,3-dihydroindene-1-carboxylic acid
InChI:InChI=1S/C10H12NO5P/c11-10(9(12)13)4-3-6-5-7(17(14,15)16)1-2-8(6)10/h1-2,5H,3-4,11H2,(H,12,13)(H2,14,15,16)
InChIKey:ZNQZXIHSJUDIKL-UHFFFAOYSA-N
SMILES:C1CC(C2=C1C=C(C=C2)P(=O)(O)O)(C(=O)O)N
Rigidified analog of MPPG; selective group II metabotropic glutamate receptor antagonist (IC50 = 30 μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses unusual inverse agonist-like action.
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