(R)-(-)-α-Methylhistamine dihydrobromide


CAS No. : 868698-49-1

(R)-(-)-α-Methylhistamine dihydrobromide,868698-49-1
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I010241
Synonyms:(R)-(-)-α-Methyl-1H-imidazole-4-ethanamine dihydrobromide
Molecular Formula:C6H13Br2N3
Molecular Weight:286.999
Target:Histamine Receptor
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Cat No:I010241
Cas No:868698-49-1
Product-Name:(R)-(-)-α-Methylhistamine dihydrobromide
IUPAC Name:(2R)-1-(1H-imidazol-5-yl)propan-2-amine;dihydrobromide
InChI:InChI=1S/C6H11N3.2BrH/c1-5(7)2-6-3-8-4-9-6;;/h3-5H,2,7H2,1H3,(H,8,9);2*1H/t5-;;/m1../s1
InChIKey:RWHNAAABSGVRDT-ZJIMSODOSA-N
SMILES:CC(CC1=CN=CN1)N.Br.Br
Very potent, high affinity H3 agonist (KD = 50.3 nM) that displays > 200-fold selectivity over H4 receptors. Inhibits H3-mediated histamine synthesis and release in the CNS and stimulates H4-mediated eosinophil shape change (EC50 = 66 nM). 
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