CAS No. : 1809249-37-3

Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I009001
Synonyms:Remdesivir; GS-5734; GS 5734; GS5734.;2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[1,2-b]pyridazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Molecular Formula:C27H35N6O8P
Molecular Weight:602.585
Price:Get quote
Inventory Status:In stock!
Tags:COVID-19 |
We would like to match the lowest price on market if possible.

Your information is safe with us.

Appearance:Solid powder
Cat No:I009001
Cas No:1809249-37-3
IUPAC Name:2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Remdesivir(cas 1809249-37-3), also known as GS-5734, is an antiviral drug, a novel nucleotide analog prodrug. It was developed by Gilead Sciences as a treatment for filovirus infections such as Ebola virus disease and Marburg virus, though it has subsequently also been found to show reasonable antiviral activity against more distantly related viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, and MERS-coronavirus. GS-5734 was rapidly pushed through clinical trials due to the 2013–2016 West African Ebola virus epidemic crisis, eventually being used in at least one human patient despite its early development stage at the time. Preliminary results have been promising, and further clinical trials are planned. 

Based on success against other coronavirus infections, Gilead provided remdesivir to physicians who treated an American patient in Snohomish County, Washington in 2020, infected with SARS-CoV-2 and is providing the compound to China to conduct a pair of trials in infected individuals with and without severe symptoms.

1: Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S. Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Nature. 2016 Mar 17;531(7594):381-5. doi: 10.1038/nature17180. PubMed PMID: 26934220.

Chem Calculators

Related Products
  • CAS No. :155213-67-5
    Product Name:


    Cat No: A000960 View details
  • CAS No. :192725-17-0
    Product Name:


    Cat No: A000587 View details
  • CAS No. :259793-96-9
    Product Name:


    Cat No: I000017 View details
  • CAS No. :1355149-45-9
    Product Name:


    Cat No: I005408 View details
Recommend Products
  • CAS No. :15057-11-1
    Product Name:


    Cat No: M053658 View details
  • CAS No. :14888-58-5
    Product Name:


    Cat No: M053659 View details
  • CAS No. :10482-65-2
    Product Name:

    cinnamyl valerate

    Cat No: M053660 View details
  • CAS No. :13025-73-5
    Product Name:


    Cat No: M053661 View details
  • CAS No. :10507-86-5
    Product Name:


    Cat No: M053663 View details
  • CAS No. :15181-41-6
    Product Name:


    Cat No: M053667 View details
  • CAS No. :14370-23-1
    Product Name:


    Cat No: M053668 View details
  • CAS No. :12738-14-6
    Product Name:

    Sodium niobate

    Cat No: M053669 View details
  • CAS No. :13918-37-1
    Product Name:

    Fayalite (Fe2(SiO4))

    Cat No: M053670 View details
  • CAS No. :14123-78-5
    Product Name:


    Cat No: M053671 View details
  • CAS No. :14176-47-7
    Product Name:

    trans-tetrahydrothiophene-3,4-diol 1,1-dioxide

    Cat No: M053672 View details
  • CAS No. :14919-38-1
    Product Name:


    Cat No: M053674 View details