Prucalopride Succinate

CAS No. : 179474-85-2 (Succinate); 179474-81-8 (free base).

Prucalopride Succinate,179474-85-2 (Succinate); 179474-81-8 (free base).
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I008890
Synonyms:R-108512; R 108512; R108512; Prucalopride Succinate; Resolor; Resotran.;4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide succinate
Molecular Formula:C22H32ClN3O7
Molecular Weight:485.962
Target:5-HT4 agonist
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Appearance:Solid powder
Purity: > 98%
Cat No:I008890
Cas No:179474-85-2 (Succinate); 179474-81-8 (free base).
Product-Name:Prucalopride Succinate
Prucalopride, also known as R-108512, is a selective, high affinity serotonin (5-HT4) receptor agonist with enterokinetic activities. Prucalopride alters colonic motility patterns via serotonin 5-HT4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation. Prucalopride was approved for use in Europe in 2009.

1:Selective separation and characterisation of stress degradation products and process impurities of prucalopride succinate by LC-QTOF-MS/MS. Mahamuni BS, Jajula A, Awasthi A, Kalariya PD, Talluri MV.J Pharm Biomed Anal. 2016 Jun 5;125:219-28. doi: 10.1016/j.jpba.2016.03.047. Epub 2016 Mar 24. PMID: 27037978
2:Prucalopride succinate for the treatment of constipation: an update. Bassotti G, Gambaccini D, Bellini M.Expert Rev Gastroenterol Hepatol. 2016;10(3):291-300. doi: 10.1586/17474124.2016.1129897. Epub 2016 Jan 29. Review. PMID: 26647167
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