(R,S)-Ivosidenib


CAS No. :

(R,S)-Ivosidenib,
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I005832
Molecular Formula:C28H22ClF3N6O3
Molecular Weight:582.96
Target:IDH1
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Cat No:I005832
Product-Name:(R,S)-Ivosidenib
(R,S)-Ivosidenib is a inhibitor of Isocitrate Dehydrogenase (IDH1). 

[1]. Agresta Samuel V, et al. (S)-N-((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide as therapeutically active compound for treating cancer characterized by a mutant allele of IDH1. From PCT Int. Appl. (2015), WO 2015127172 A1 20150827. 

[2]. Gu Chong-Hui, et al. Pharmaceutical compositions of therapeutically active compounds comprising (S)-N-((S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide for treating hematologic malignancies with mutant allele of IDH1. From PCT Int. Appl. (2015), WO 2015138839 A1 20150917.

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