Appearance:Solid powder
Purity: > 98%
| Cat No: | I005226 |
| Cas No: | 869113-09-7 |
| Product-Name: | Umeclidinium bromide |
| IUPAC Name: | diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol;bromide |
| InChI: | InChI=1S/C29H34NO2.BrH/c31-29(26-12-6-2-7-13-26,27-14-8-3-9-15-27)28-16-19-30(20-17-28,21-18-28)22-23-32-24-25-10-4-1-5-11-25;/h1-15,31H,16-24H2;1H/q+1;/p-1 |
| InChIKey: | PEJHHXHHNGORMP-UHFFFAOYSA-M |
| SMILES: | OC(C1=CC=CC=C1)(C2=CC=CC=C2)C34CC[N+](CC4)(CCOCC5=CC=CC=C5)CC3.[Br-] |
Umeclidinium bromide(GSK573719A, CAS 869113-09-7) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD).
1: Ni H, Htet A, Moe S. Umeclidinium bromide versus placebo for people with chronic obstructive pulmonary disease (COPD). Cochrane Database Syst Rev. 2017 Jun 20;6:CD011897. doi: 10.1002/14651858.CD011897.pub2. Review. PubMed PMID: 28631387.
2: Ismaila A, Huisman E, Punekar YS. Comparative Efficacy of Umeclidinium Bromide Versus Other Long-Acting Anticholinergic Monotherapies as Treatments for Copd Patients. Value Health. 2014 Nov;17(7):A588-9. doi: 10.1016/j.jval.2014.08.2013. Epub 2014 Oct 26. PubMed PMID: 27202005.
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