(+)-Bicuculline


CAS No. : 485-49-4

(+)-Bicuculline,485-49-4
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I003708
Synonyms:NSC 32192
Molecular Formula:C20H17NO6
Molecular Weight:367.4
Target:GABAA receptor
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Melting Point:192-196 °C
Appearance:Powder
Optical Activity:Not determined
Purity:98 %
Cat No:I003708
Cas No:485-49-4
Product-Name:(+)-Bicuculline
InChIKey:IYGYMKDQCDOMRE-ZWKOTPCHSA-N

(+)-Bicuculline, a convulsant alkaloid, is the antagonist of GABA.


[1]. Zahm DS, et al. Comparison of the locomotor-activating effects of bicuculline infusions into the preoptic area and ventral pallidum. Brain Struct Funct. 2014 Mar;219(2):511-26.
[2]. Johnston GA. Advantages of an antagonist: bicuculline and other GABA antagonists. Br J Pharmacol. 2013 May;169(2):328-36.
[3]. Graham AR Johnston. Advantages of an antagonist: bicuculline and other GABA antagonists. Br J Pharmacol. 2013 May; 169(2): 328–336.

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