(S)-(-)-5-Fluorowillardiine


CAS No. : 140187-23-1

(S)-(-)-5-Fluorowillardiine,140187-23-1
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I001533
Synonyms:(S)-2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid
Molecular Formula:C7H8FN3O4
Molecular Weight:217.16
Target:AMPAR
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Cat No:I001533
Cas No:140187-23-1
Product-Name:(S)-(-)-5-Fluorowillardiine

(S)-(-)-5-Fluorowillardiine is a potent and specific AMPAR agonist.


[1]. Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21.
[2]. Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41.
[3]. Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82.

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