CAS No. : 108212-76-6

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For research use only. Not Intended for Therapeutic Use!
Cat No:I000357
Molecular Formula:C57H76IN3O22S4
Molecular Weight:1410.39
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Cat No:I000357
Cas No:108212-76-6

N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic.
Target: Antibacterial
N-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.

[1]. Stasi R, et al. Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia. Cancer Treat Rev. 2008 Feb;34(1):49-60.

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