Ginsenoside Rh3

CAS No. : 105558-26-7

Ginsenoside Rh3,105558-26-7
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000289
Molecular Formula:C36H60O7
Molecular Weight:604.86
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Cat No:I000289
Cas No:105558-26-7
Product-Name:Ginsenoside Rh3

Ginsenoside Rh3, metabolized from ginsenoside Rg5 which is isolated from red ginseng can be anti-inflammatory.
IC50 value:
In vitro: Ginsenoside Rh3 can induce differentiation of HL-60 cells into granulocytes and modulation of PKC isoform levels may contribute to differentiation of HL-60 cells by G-Rh2 [2].
In vivo: Ginsenoside Rh3 suppressed swelling of oxazolone-induced mouse ear contact dermatitis, reduced mRNA expressions of cyclooxygenase-2, interleukin (IL)-1beta, tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma [1].

[1]. Shin YW, et al. Inhibitory effect of ginsenoside Rg5 and its metabolite ginsenoside Rh3 in an oxazolone-induced mouse chronic dermatitis model. Arch Pharm Res. 2006 Aug;29(8):685-90.
[2]. Kim YS, et al. Ginsenoside Rh2 and Rh3 induce differentiation of HL-60 cells into granulocytes: modulation of protein kinase C isoforms during differentiation by ginsenoside Rh2. The international journal of biochemistry & cell biology, 1998, 30 (3): 327-338

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