RU-SKI 43


CAS No. : 1043797-53-0

RU-SKI 43,1043797-53-0
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000249
Synonyms:2-((2-methylbutyl)amino)-1-(4-((m-tolyloxy)methyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanone
Molecular Formula:C22H30N2O2S
Molecular Weight:386.55
Target:Hedgehog
Price:Get quote
We would like to match the lowest price on market if possible.

Your information is safe with us.

refresh
Cat No:I000249
Cas No:1043797-53-0
Product-Name:RU-SKI 43

RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.
IC50 value:
Target: Hhat inhibitor
RU-SKI 43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.


[1]. Petrova E, et al. Hedgehog acyltransferase as a target in pancreatic ductal adenocarcinoma. Oncogene. 2014 Jan 27. doi: 10.1038/onc.2013.575.

Related Products
  • CAS No. :3039-71-2
    Product Name:

    U-18666A

    Cat No: I010437 View details
  • CAS No. :329196-48-7
    Product Name:

    SANT-2

    Cat No: I010794 View details
  • CAS No. :516-72-3
    Product Name:

    20α-Hydroxy Cholesterol

    Cat No: R001076 View details
  • CAS No. :304909-07-7
    Product Name:

    SANT-1

    Cat No: I011873 View details