CAS No. : 103909-75-7

Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000234
Molecular Formula:C26H42O4
Molecular Weight:418.6
Price:Get quote
We would like to match the lowest price on market if possible.

Your information is safe with us.


Appearance:A crystalline solid
Cat No:I000234
Cas No:103909-75-7

Maxacalcitol (22-Oxacalcitriol) is non-calcemic vitamin D3 analog and ligand of VDR-like receptors.
IC50 value:
Maxacalcitol (22-Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol exhibits similar effects to calcitriol in osteoblast-like cells. Maxacalcitol(22-Oxacalcitriol) inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.

[1]. Monier-Faugere et al 22-Oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. Kidney Int. (1999)55 821.
[2]. Barroga et al Inhibitory effects of 22-oxa-calcitriol and all-trans retinoic acid on the growth of a canine osteosarcoma derived cell-line in vivo and its pulmonary metastasis in vivo. Res.Vet.Sci. (2000)68 79.
[3]. Inoue K, Matsui I, Hamano T, Fujii N, Shimomura A, Nakano C, Kusunoki Y, Takabatake Y, Hirata M, Nishiyama A, Tsubakihara Y, Isaka Y, Rakugi H.Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.Lab Invest. 2012 Aug 27.
[4]. Karashima T, Hashikawa K, Ono F, Eguchi H, Hamada T, Ishii N, Dainichi T, Yasumoto S, Tsuruta D, Hashimoto T.Successful Treatment of Bowen/'s Disease with Topical Maxacalcitol.Acta Derm Venereol. 2012 Jan 26.

Related Products
  • CAS No. :511-28-4
    Product Name:

    Vitamin D4

    Cat No: I003831 View details
  • CAS No. :
    Product Name:


    Cat No: I005880 View details
  • CAS No. :126860-83-1
    Product Name:

    MC 1046

    Cat No: I001077 View details
  • CAS No. :55721-11-4
    Product Name:


    Cat No: I004076 View details