2-AEMP TFA


CAS No. : 321882-95-5

2-AEMP TFA,321882-95-5
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000222
Synonyms:2-AEMP TFA; 2AEMP TFA; 2 AEMP TFA; 2-AEMP; 2 AEMP; 2AEMP;2-Aminoethyl methylphosphonate trifluoroacetate salt
Molecular Formula:C5H10F3NO5P-5P
Molecular Weight:252.11
Target:GABA(A)-ρ1 receptor antagonist
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Appearance:Solid powder
Purity: > 98%
Cat No:I000222
Cas No:321882-95-5
Product-Name:2-AEMP TFA
InChI:InChI=1S/C3H10NO3P.C2HF3O2/c1-8(5,6)7-3-2-4;3-2(4,5)1(6)7/h2-4H2,1H3,(H,5,6);(H,6,7)/p-1
InChIKey:RFQBFVSSBOQLIQ-UHFFFAOYSA-M
SMILES:CP(OCCN)([O-])=O.O=C(O)C(F)(F)F
2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.

1: Xie A, Yan J, Yue L, Feng F, Mir F, Abdel-Halim H, Chebib M, Le Breton GC, Standaert RF, Qian H, Pepperberg DR. 2-Aminoethyl methylphosphonate, a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. Mol Pharmacol. 2011 Dec;80(6):965-78. doi: 10.1124/mol.111.071225. Epub 2011 Aug 2. PubMed PMID: 21810922; PubMed Central PMCID: PMC3228531.
2: Wang J, Mojumder DK, Yan J, Xie A, Standaert RF, Qian H, Pepperberg DR, Frishman LJ. In vivo electroretinographic studies of the role of GABAC receptors in retinal signal processing. Exp Eye Res. 2015 Oct;139:48-63. doi: 10.1016/j.exer.2015.07.002. Epub 2015 Jul 8. PubMed PMID: 26164072; PubMed Central PMCID: PMC4573340.

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