Calyculin A

CAS No. : 101932-71-2

Calyculin A,101932-71-2
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000139
Molecular Formula:C₅₀H₈₁N₄O₁₅P
Molecular Weight:1009.17
Target:Protein Ser/Thr Phosphatases
Price:Get quote
We would like to match the lowest price on market if possible.

Your information is safe with us.


Appearance:A solid
Cat No:I000139
Cas No:101932-71-2
Product-Name:Calyculin A
MDL No:MFCD06795864

Calyculin A is a potent inhibitor of the catalytic subunit of type-2A phosphatase, with IC50 values of 0.5 to 1 nM.
Target: protein phosphatase
Calyculin A induces contraction in smooth muscle fibers. With the catalytic subunit of protein phosphatase type-1, calyculin A is an effective inhibitor , IC50 values for calyculin A is about 2 nM and. The endogenous phosphatase of smooth muscle myosin B was inhibited by calyculin A with IC50 values of 0.3 to 0.7 nM for calyculin A. The partially purified catalytic subunit from myosin B had IC50 values of 0.7 nM for calyculin A.

[1]. Ishihara H, et al. Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem Biophys Res Commun. 1989 Mar 31;159(3):871-7.

Related Products
  • CAS No. :893449-38-2
    Product Name:

    PRL-3 Inhibitor

    Cat No: I011769 View details
  • CAS No. :1026680-07-8
    Product Name:


    Cat No: I011774 View details
  • CAS No. :1465-77-6
    Product Name:

    disodium cantharidin

    Cat No: M048647 View details
  • CAS No. :81525-10-2
    Product Name:


    Cat No: I004959 View details