Oxfendazole


CAS No. : 53716-50-0

Oxfendazole,53716-50-0
Product Details
Cat No:A001223
Synonyms:RS-8858
Molecular Formula:C15H13N3O3S
Molecular Weight:315.35
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Cat No:A001223
Cas No:53716-50-0
Product-Name:Oxfendazole
Oxfendazole is a broad spectrum benzimidazole anthelmintic.
Oxfendazole (OX) induces not only mRNA expression of phase I enzymes Cyp1a1, Cyp1a2, but also Nrf2-regulated phase II enzymes such as Gpx2, Nqo1, Yc2, Akr7a3 and Gstm1 in rats, presumably due to an adaptive response against OX-induced oxidative stress. Oxfendazole enhances oxidative DNA damage (as assessed by 8-hydroxydeoxyguanosine; 8-OHdG) and lipid peroxidation (as assessed by thiobarbituric acid-reactive substances; TBARS) in rats.
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