Tylosin tartrate


CAS No. : 74610-55-2

Tylosin tartrate,74610-55-2
Product Details
Cat No:A001141
Synonyms:NA
Molecular Formula:C46H77NO17.C4H6O6
Molecular Weight:1066.19
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Form:Powder
Appearance:Almost white or slightly yellow powder
pH:5.0 - 7.2
Assay:Not less than 800 IU/mg (on dried basis)
Loss on Drying:≤4.5%
Sulfated Ash:≤2.5%
Impurities:Tyramine: ≤3.5%
Cat No:A001141
Cas No:74610-55-2
Product-Name:Tylosin tartrate
Tylosin tartrate is a bacteriostatic macrolide antibiotic and is freely soluble in aqueous solution.
Macrolide antibiotics inhibit bacterial growth by targeting the 50S ribosomal subunit preventing peptide bond formation and translocation during protein synthesis. Resistance to tylosin tartate is commonly attributed to mutations in 50S rRNA preventing tylosin tartate binding allowing the cell to synthesize proteins free of error.

Lovmar, Martin, and Tanel Tenson. /The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome./Journal of Molecular Microbiology 330.5 (2003): 1005-014.

 

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