| Cat No: | A001015 |
| Cas No: | 163253-35-8 |
| Product-Name: | Sitafloxacin Hydrate |
Sitafloxacin sesquihydrate is a broad-spectrum fluoroquinoline antibiotic that is particularly active against gram-positive bacteria such as a pneumococci.Sitafloxacin has been shown to have a dual targeted mechanism of action. Other antibacterial quinolones target DNA gyrase or topoisomerase IV, but sitafloxacin targets both at a very similar rate. This double-target approach lowers the possibility of resistant strains.
Onodera, Y., Uchida, Y., Tanaka, M., & Sato, K. (1999). Dual inhibitory activity of sitafloxacin (DU-6859a) against DNA gyrase and topoisomeraseIV of Streptococcus pneumoniae. Journal Of Antimicrobial Chemotherapy, 44(4), 533-536. http://dx.doi.org/10.1093/jac/44.4.533
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