Quinine Hydrochloride Dihydrate

CAS No. : 6119-47-7

Quinine Hydrochloride Dihydrate,6119-47-7
Product Details
Cat No:A000470
Synonyms:(8α,9R)-6’-Methoxycinchonan-9-ol Monohydrochloride Dihydrate; Quinine Hydrochloride Dihydrate;
Molecular Formula:C20H24N2O2.HCl.2H2O
Molecular Weight:396.91
Target:Potassium channel
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Inventory Status:In Stock
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Appearance: White Solid
Purity: 98.0%
Cat No:A000470
Cas No:6119-47-7
Product-Name:Quinine Hydrochloride Dihydrate
MDL No:MFCD00151248
Quinine hydrochloride dihydrate(cas 6119-47-7 ) is a white crystalline K+ channel blocker, used to treat malaria. It is a stereoisomer of of quinidine which contains an aromatic quinoline and a bicyclic quinuclidine.
1: Karle JM, Karle IL. Structure of 9-epiquinine hydrochloride dihydrate versus antimalarial activity. Acta Crystallogr C. 1992 Nov 15;48 ( Pt 11):1975-80. PubMed PMID: 1457075.
2: Immohr LI, Turner R, Pein-Hackelbusch M. Impact of sodium lauryl sulfate in oral liquids on e-tongue measurements. Int J Pharm. 2016 Dec 30;515(1-2):441-448. doi: 10.1016/j.ijpharm.2016.10.045. Epub 2016 Oct 21. PubMed PMID: 27777034.
3: Bezáková Z, Stankovičová M. [Alkalimetric titrations of salts of organic bases in the Pharmacopoeia]. Ceska Slov Farm. 2013 Dec;62(6):264-9. Czech. PubMed PMID: 24393115.
4: Fuchida S, Yamamoto T, Takiguchi T, Kandaudahewa G, Yuyama N, Hirata Y. Association between underweight and taste sensitivity in middle- to old-aged nursing home residents in Sri Lanka: a cross-sectional study. J Oral Rehabil. 2013 Nov;40(11):854-63. doi: 10.1111/joor.12099. Epub 2013 Sep 20. PubMed PMID: 24111976.
5: Soto J, Sheng Y, Standing JF, Orlu Gul M, Tuleu C. Development of a model for robust and exploratory analysis of the rodent brief-access taste aversion data. Eur J Pharm Biopharm. 2015 Apr;91:47-51. doi: 10.1016/j.ejpb.2015.01.016. Epub 2015 Jan 22. PubMed PMID: 25619919.
6: Karle JM, Karle IL, Gerena L, Milhous WK. Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum. Antimicrob Agents Chemother. 1992 Jul;36(7):1538-44. PubMed PMID: 1510452; PubMed Central PMCID: PMC191617.
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