Clindamycin hydrochloride


CAS No. : 21462-39-5

Clindamycin hydrochloride,21462-39-5
Product Details
Cat No:A000180
Molecular Formula:C₁₈H₃₃ClN₂O₅S · HCl
Molecular Weight:461.44
Target:50S ribosomal
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Appearance:White solid
Purity:98%(HPLC)
Cat No:A000180
Cas No:21462-39-5
Product-Name:Clindamycin hydrochloride
MDL No:MFCD07793327
InChI:InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
InChIKey:AUODDLQVRAJAJM-XJQDNNTCSA-N
SMILES:CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl
Clindamycin hydrochloride is a salt of clindamycin, a semi-synthetic lincosamide. The hydrochloride salt forms at the basic Nethylproline moiety and is the preferred pharmaceutical formulation. Like other members of the lincosamide family, clindamycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin hydrochloride acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin hydrochloride has been extensively studied with over 8,000 literature citations.

Lovmar, Martin, and Tanel Tenson. /The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome./Journal of Molecular Microbiology 330.5 (2003): 1005-014.

 

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