18-Crown-6

• CAT Number: R050682
• CAS Number: 17455-13-9
• Molecular Formula: C12H24O6
• Molecular Weight: 264.32
• Purity: 98%
• Synonyms: 18-Crown-6 ether; Ethylene Oxide Cyclic Hexamer; 1,4,7,10,13,16-Hexaoxacyclooctadecane; NSC 159836
• Storage: -20°C
• IUPAC Name: 1,4,7,10,13,16-hexaoxacyclooctadecane
• InChI: InChI=1S/C12H24O6/c1-2-14-5-6-16-9-10-18-12-11-17-8-7-15-4-3-13-1/h1-12H2
• InChIKey: XEZNGIUYQVAUSS-UHFFFAOYSA-N
• SMILES: C1COCCOCCOCCOCCOCCO1

18-Crown-6（Cat No.:R050682）is a cyclic polyether with the molecular formula C₁₂H₂₄O₆, consisting of a ring of twelve carbon atoms and six oxygen atoms. Its structure allows it to selectively bind metal cations, especially potassium (K⁺), by coordinating through its oxygen atoms. This crown ether is widely used in phase-transfer catalysis, ion transport studies, and coordination chemistry. It enhances the solubility of ionic compounds in organic solvents and facilitates nucleophilic substitution reactions. 18-Crown-6 is a white crystalline solid, soluble in polar organic solvents, and plays a vital role in supramolecular and host–guest chemistry.