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Pim1 AKK1-IN-1 CAS: 1093222-27-5

Category: Inhibitors
Product Name: Pim1 AKK1-IN-1
Cat No: I000393
CAS No: 1093222-27-5
Synonyms: N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide
Molecular Formula: C20H13N5O
Molecular Weight: 339.36
Solubility: 10 mM in DMSO
Target: Pim
Storage: Store at -20°C
CAS 1093222-27-5,Pim1 AKK1-IN-1
  • Description

PIM/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively; also inhibits MPSK1 and TNIK.

  • References

[1]. Bamborough P, et al. Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem. 2008 Dec 25;51(24):7898-914.

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