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AEBSF HCl CAS: 30827-99-7 (HCl)

Category: Inhibitors
Product Name: AEBSF HCl
Cat No: I000372
CAS No: 30827-99-7 (HCl)
Synonyms: AEBSF hydrochloride; AEBSF HCl.;4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride
Molecular Formula: C8H11ClFNO2S
Molecular Weight: 239.6894
MDL No: MFCD00132962
SMILES: O=S(C1=CC=C(CCN)C=C1)(F)=O.[H]Cl
InChI: InChI=1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
InChIKey: WRDABNWSWOHGMS-UHFFFAOYSA-N
Solubility: Soluble in DMSO
Target: serine protease inhibitor
Storage: 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months).
CAS 30827-99-7 (HCl),AEBSF HCl
  • Description

AEBSF is a specific irreversible serine protease inhibitor. AEBSF inhibits the rat embryo implantation in vivo and interferes with cell adhesion in vitro. Both AEBSF and PMSF are sulfonyl fluorides and are sulfonylating agents. Sulfonyl fluorides act by reacting with the hydroxy group of the active site serine residue to form a sulfonyl enzyme derivative. This derivative may be stable for long periods of time except at high pH.

  • Spec

Appearance:Solid powder
Purity: > 98%

  • References


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11: Park IC, Park MJ, Choe TB, Jang JJ, Hong SI, Lee SH. TNF-alpha induces apoptosis mediated by AEBSF-sensitive serine protease(s) that may involve upstream caspase-3/CPP32 protease activation in a human gastric cancer cell line. Int J Oncol. 2000 Jun;16(6):1243-8. PubMed PMID: 10812002.
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price inquiry for CAS:30827-99-7 (HCl), Product:AEBSF HCl